BOC-L-THREONINE extrapure
BOC-L-Threonine
CAS: 2592-18-9
Molecular Formula: C9H17NO5
BOC-L-THREONINE extrapure - Names and Identifiers
| Name | BOC-L-Threonine |
| Synonyms | Boc-Thr-OH BOC-L-THREONINE BOC-L-Threonine Boc-L-Threionine N-Boc-L-threonine BOC-L-THREONINE extrapure N-T-BOC-L-THREONINE CRYSTALLINE N-(tert-butoxycarbonyl)threonine N-(tert-Butoxycarbonyl)-L-threonine N-ALPHA-T-BUTYLOXYCARBONYL-L-THREONINE N-(tert-Butoxycarbonyl)-L-threonine, Boc-L-threonine (2S,3R)-2-[(tert-butoxycarbonyl)amino]-3-hydroxybutanoate |
| CAS | 2592-18-9 |
| EINECS | 219-987-6 |
| InChI | InChI=1/C9H17NO5/c1-5(11)6(7(12)13)10-8(14)15-9(2,3)4/h5-6,11H,1-4H3,(H,10,14)(H,12,13)/p-1/t5-,6+/m1/s1 |
BOC-L-THREONINE extrapure - Physico-chemical Properties
| Molecular Formula | C9H17NO5 |
| Molar Mass | 219.24 |
| Density | 1.2470 (rough estimate) |
| Melting Point | 80-82°C(lit.) |
| Boling Point | 360.05°C (rough estimate) |
| Specific Rotation(α) | -8.5 º (c=1, acetic acid) |
| Flash Point | 187.9°C |
| Vapor Presure | 1.36E-07mmHg at 25°C |
| Appearance | White amorphous powder |
| Color | White to Almost white |
| BRN | 2331474 |
| pKa | 3.60±0.10(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | -7 ° (C=1, AcOH) |
| MDL | MFCD00065946 |
BOC-L-THREONINE extrapure - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29241990 |
BOC-L-THREONINE extrapure - Reference Information
| Uses | Boc-L-threonine is an amino acid derivative and can be used as a biochemical reagent. |
| application | Boc-L-threonine is mainly used in polypeptide synthesis, mainly used in a variety of drugs and biotechnology applications. Threonine has a wide range of uses and functions. In the prior art, Boc is used as a protecting group to protect L-threonine. Boc-L-threonine is an important intermediate raw material for many kinds of medicine and biotechnology. |
| preparation | 1. add 15.8gL-threonine, add 200ml of 0.0005mol/L potassium bicarbonate solution, stir and dissolve, then add 8g of (Boc)2O for reaction for 2 hours, then add 8g of (Boc)2O for reaction for 2 hours, and finally add 9g of (Boc)2O for reaction for 2 hours. 2. After adjusting PH = 3 with 0.001mol/L hydrochloric acid, use tert-butyl acetate 0.4L/time to extract the product three times. Combine ester layers and wash with brine to neutral. Add 15 grams of anhydrous sodium sulfate and dry for 8 hours. 3. Filter, concentrate and dry the filtrate under reduced pressure, add 50ml petroleum ether, stir and crystallize. Centrifuge out the product and dry it. The product 22.4g is obtained. The yield is 91.73%. |
Last Update：2024-04-09 21:32:04
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Product Name: BOC-L-Threonine Visit Supplier Webpage Request for quotationCAS: 2592-18-9
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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